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UK-Förderung (691.642 £): Auf dem Weg zu einem universellen biologischen Zellbetriebssystem (AUdACiOuS) Ukri 01.01.2014 Forschung und Innovation im Vereinigten Königreich, Großbritannien

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Auf dem Weg zu einem universellen biologischen Zellbetriebssystem (AUdACiOuS)

Zusammenfassung A living cell, e.g. a bacterium, is an information-processing machine. It is composed of a series of sub-systems that work in concert by sensing external stimuli, assessing its own internal states and making decisions through a network of complex and interlinked biological regulatory networks (BRN) motifs that act as the bacterium neural network. A bacterium's decision making processes often result in a variety of outputs, e.g. the creation of more cells, chemotaxis, bio-film formation, etc. It was recently shown that cells not only react to their environment but that they can even predict environmental changes. The emerging discipline of Synthetic Biology (SB), considers the cell to be a machine that can be built -from parts- in a manner similar to, e.g., electronic circuits, airplanes, etc. SB has sought to co-opt cells for nano-computation and nano-manufacturing purposes. During this leadership fellowship programme of research I will aim at making E.coli bacteria much more easily to program and hence harness for useful purposes. In order to achieve this, I plan to use the tools, methodologies and resources that computer science created for writing computer programs and find ways of making them useful in the microbiology laboratory.
Kategorie Fellowship
Referenz EP/J004111/2
Status Closed
Laufzeit von 01.01.2014
Laufzeit bis 31.12.2017
Fördersumme 691.642,00 £
Quelle https://gtr.ukri.org/projects?ref=EP%2FJ004111%2F2

Beteiligte Organisationen

Newcastle University
Michigan State University
Massachusetts Institute of Technology
Weizmann Institute of Science
University of California Santa Barbara
Arizona State University
University of Edinburgh
Spanish National Research Council (CSIC)
New York University
University of California, San Francisco

Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider. Der letzte verfügbare Stand wird auf folgender Seite wiedergegeben: Newcastle University, Newcastle Upon Tyne, Großbritannien.