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UK-Förderung (88.229 £): Enzyme co-localisation and aggregation for enhanced metabolic activity for commodity chemicals. Ukri01.09.2016 Forschung und Innovation im Vereinigten Königreich, Großbritannien
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Enzyme co-localisation and aggregation for enhanced metabolic activity for commodity chemicals.
Zusammenfassung | Current approaches for enhancing bio-based commodity production are restricted to known biosynthetic pathways and limitations to metabolite toxicity. However, many key bio-commodities are made via aldehyde-intermediates such as acetaldehyde, lactaldehyde and propanaldehyde and their production is often limited because of the inherent toxicity of their chemical reactivity. Ways to reduce this toxicity would offer a significant advantage to the commercial production of these materials. This application outlines a major new strategy to reduce the toxicity of key metabolic intermediates such as acetaldehyde through the deployment of proteinaceous scaffolds. This approach will be coupled to a novel pathway that will be engineered in specific bacteria called acetogens that can live on gaseous exhaust fumes in order to produce a key chemical commodity called 1,3-butanediol. |
Kategorie | Feasibility Studies |
Referenz | 132326 |
Status | Closed |
Laufzeit von | 01.09.2016 |
Laufzeit bis | 30.11.2017 |
Fördersumme | 88.229,00 £ |
Quelle | https://gtr.ukri.org/projects?ref=132326 |
Beteiligte Organisationen
Zuvasyntha Limited |
88.229,00 £ |
University of Kent |
Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider. Der aktuelle Stand wird auf folgender Seite wiedergegeben: Zuvasyntha Ltd., Knebworth, Großbritannien.
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