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UK-Förderung (635.663 £): Molekulare Analyse von SMC-Proteinen (Structural Maintenance of Chromosome) am Kinetochor Ukri29.04.2009 Forschung und Innovation im Vereinigten Königreich, Großbritannien
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Molekulare Analyse von SMC-Proteinen (Structural Maintenance of Chromosome) am Kinetochor
| Zusammenfassung | Cell division is a remarkable process in which a cell grows and divides to form two identical daughter cells. For this to occur, cell has to accomplish two major tasks a) Duplicate the DNA ( DNA replication) b) Segregate the duplicated DNA molecules equally to the 2 daughter cells( chromosome segregation). Mistakes in either process can lead to cancer and disease in humans. Structural maintenance of chromosome (SMC) proteins is a family of proteins conserved from bacteria to humans and essential for accurate chromosome segregation.. Members of the SMC family play crucial roles in organizing the higher order structure of chromosomes. But the precise function of these proteins are poorly understood. Our research aims to uncover the function of this important class of proteins using the 'baker's yeast' as the model system. Since cell division is vital for all forms of life mechanisms that mediate high-fidelity chromosome segregation are generally conserved from yeast to humans. |
| Kategorie | Research Grant |
| Referenz | BB/G00353X/1 |
| Status | Closed |
| Laufzeit von | 29.04.2009 |
| Laufzeit bis | 28.08.2013 |
| Fördersumme | 635.663,00 £ |
| Quelle | https://gtr.ukri.org/projects?ref=BB%2FG00353X%2F1 |
Beteiligte Organisationen
| University of Warwick |
Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider. Der aktuelle Stand wird auf folgender Seite wiedergegeben: University of Warwick, Coventry, Großbritannien.
