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EU-Förderung (2.672.562 €): Der Lebenszyklus von extrazellulären Vesikeln bei Prostatakrebs: von Biogenese und Homing bis hin zur funktionellen Relevanz Hor 13.08.2019 EU-Rahmenprogramm für Forschung und Innovation "Horizont"

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Der Lebenszyklus von extrazellulären Vesikeln bei Prostatakrebs: von Biogenese und Homing bis hin zur funktionellen Relevanz

The prostate cancer Extracellular Vesicle LifeCycle (proEVLifeCycle) network is an innovative, multidisciplinary training program focused on understanding the biology, biomarker potential and function of extracellular vesicles (EVs) to resolve unmet clinical needs of prostate cancer (PCa). It is within this realm, that we will equip early stage researchers with the knowledge, tools and a creative ethos to be independent scientists, leaders, and drivers of innovation. The lifecycle of EVs is poorly understood and their potential as non-invasive biomarkers and therapy target/agents, a growing area of interest. This research can perfectly be integrated with the high need for novel biomarkers and therapy targets for PCa. Any relief in the burden of this disease will have major impact on the huge socio-economic problems for patients, families, caregivers and society. The ambitious scientific objectives are to unravel the mysteries of EV biogenesis, homing and uptake to explain how vesicles operate in disease processes; their heterogeneity, their molecular complexity, the biological functions they drive, their local and systemic dissemination and how these may be manipulated. Using state-of-the-art, network-wide shared model systems, imaging and profiling tools, and systems biology, the program will enlighten the lifecycle of EVs and identify novel EV biomarkers and PCa therapy targets to address the unmet clinical needs. Our original network of 7 academic and 3 company beneficiaries and 11 partners, provides optimal scientific training, crosssectoral awareness, entrepreneurship skills, communication in the modern age, extensive opportunities for mobility and patient-facing experiences. We herein meet identified EU-skills gaps providing well-rounded and inventive experts primed for influential careers, contributing to patient well-being and economic prosperity within the EU.


Geförderte Unternehmen:

Firmenname Förderungssumme
AIT Austrian Institute OF Technology GmbH 264.207 €
Anaxomics Biotech SL 250.905 €
Asociacion Centro de Investigacion CRL en Biociencias 250.905 €
Cardiff University 303.173 €
Erasmus Universitair Medisch Centrum Rotterdam 265.620 €
Fundacion Sector Publico Estatal Centro Nacional Investigaciones Oncologicas Carlos III 250.905 €
GenomeScan B.V. 265.620 €
Institut National de la Sante et de la Recherche Medicale 274.802 €
Turun Yliopisto 280.806 €
Universitair Medisch Centrum Utrecht 265.620 €

Quelle: https://cordis.europa.eu/project/id/860303

Diese Bekanntmachung wurde von Englisch nach Deutsch übersetzt. Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider.