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EU-Förderung (3.956.399 €): Förderung der Patientensicherheit durch eine neuartige Kombination von Bildgebungstechnologien für biologisch abbaubare Magnesiumimplantate Hor01.10.2018 EU-Rahmenprogramm für Forschung und Innovation "Horizont"

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Förderung der Patientensicherheit durch eine neuartige Kombination von Bildgebungstechnologien für biologisch abbaubare Magnesiumimplantate

Biomedical imaging has gained a significant technological push and is the mainstay for diag-nosis and therapy monitoring. Still, imaging is yet not optimized for the new class of biode-gradable Mg-based implants. MgSafe addresses this point by training 15 ESRs in both, imag-ing and implant technologies. All ESRs will develop their individual Personal Learning Envi-ronment (PLE) and be trained based on the “T-skills concept” in technologies and transferable skills relevant for their career development and prepared to take over leadership positions in an area of tremendous research promises and clinical relevance where the lack for experts is severe and very well recognized. The ESRs will quantify the physical impact and suitability of a variety of modalities on Mg implants. Highly sophisticated imaging techniques (nano and µCT, MRT, PET, USPA, IR) will be developed beyond the forefront of medical device production in vivo and with in situ label-ling options to deliver non-invasively data on different time and length scales of the body reac-tion and material behavior during Mg degradation with a precision and plethora of details which is currently not available. Two Mg-alloys and CE-certified Mg-implants will be studied in rats and sheep. Dummy studies will be performed in parallel (following ASTM rules). The ob-tained multimodal imaging data will be combined with molecular biological/biochemical analy-sis, thereby increasing the information about physiological changes without using additional animals. An additional dimension will be added by the analysis of explants to obtain highest resolution chemical and material science data. All relevant biological and chemical in vivo and ex vivo data will be merged by computational 3D methods, simulations and machine learning approaches. The combination of these results will not only allow for an upscaling of the pro-cesses towards humans but will also deliver valuable data in terms of patient safety.


Geförderte Unternehmen:

Firmenname Förderungssumme
BRI.Tech GmbH ?
Consiglio Nazionale Delle Ricerche 522.999 €
Fujifilm Sonosite B.V. 265.620 €
Goeteborgs Universitet 281.983 €
Helmholtz-Zentrum Hereon GmbH 505.577 €
Medizinische Hochschule Hannover 252.788 €
Medizinische Universitat Graz 528.414 €
MRI. Tools GmbH 252.788 €
Oslomet - Storbyuniversitetet 292.342 €
Politechnika Warszawska 227.479 €
Scanco Medical AG 281.277 €
Syntellix AG 252.788 €
Universitetet I Oslo 292.342 €

Quelle: https://cordis.europa.eu/project/id/811226

Diese Bekanntmachung wurde von Englisch nach Deutsch übersetzt. Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider. Der letzte verfügbare Stand wird auf folgender Seite wiedergegeben: Bioretec GmbH, Keutschach am See, Österreich.