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EU-Förderung (3.503.923 €): A STEP FORWARD TO SPINAL CORD INJURY REPAIR USING INNOVATIVE STIMULATED NANOENGINEERED SCAFFOLDS Hor08.02.2019 EU-Rahmenprogramm für Forschung und Innovation "Horizont"

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A STEP FORWARD TO SPINAL CORD INJURY REPAIR USING INNOVATIVE STIMULATED NANOENGINEERED SCAFFOLDS

Spinal cord injury (SCI) is a devastating pathology with dramatic lifetime consequences affecting thousands of people worldwide. Therefore, and considering the very limited regeneration ability of the central nervous system, in this project we propose to develop a neural tissue engineered scaffold capable of not only combining fibrous and porous topographic cues in order to mimic the morphology of the native spinal cord, but also potentiating the properties of graphene related materials (GRM) supported in a protein-rich decellularized matrix (adECM). In fact, the suggested 3D microenvironment should present electrical, chemical, mechanical and topographic features able to preserve neural cell survival and enhance neural progenitor cell differentiation towards neuronal and glial cells. Progress in this sense will contribute to a better understanding of the key factors controlling repair in damaged neural tissues and, consequently, bring insights into new therapeutic approaches for spinal cord recovery.


Geförderte Unternehmen:

Firmenname Förderungssumme
Fundacion Tecnalia Research & Innovation 727.163 €
Graphenest SA 208.750 €
Idryma Technologias Kai Erevnas 338.375 €
Stemmatters, Biotecnologia e Mediciina Regenerativa SA 403.125 €
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM 400.767 €
STICHTING RADBOUD UNIVERSITEIT 99.233 €
Universidad Complutense de Madrid 251.250 €
Universidade de Aveiro 1.075.260 €

Quelle: https://cordis.europa.eu/project/id/829060

Diese Bekanntmachung wurde von Englisch nach Deutsch übersetzt. Die Bekanntmachung bezieht sich auf einen vergangenen Zeitpunkt, und spiegelt nicht notwendigerweise den heutigen Stand wider.